PhD Position in Nanomedicine Formulation Engineering (Cancer Treatment)

TL;DR

PhD Position in Nanomedicine Formulation Engineering (Nanomedicine): Developing innovative formulation strategies for lipid-based drug delivery nanoparticles for cancer treatment with an accent on externally triggerable nanomedicines. Focus on combining coarse-grained molecular dynamics (CGMD) simulations with empirical validation of nanoparticle stability and ultrasound-triggerability.

Location: Delft, Netherlands. Relocation support provided.

Salary: €3,059 - €3,881 gross per month

Company

hirify.global is a leading technical university dedicated to pioneering research and education to solve global challenges in science and engineering.

What you will do

• Design and optimize lipid-based nanoparticle formulations to enhance stability and performance.
• Develop strategies for externally triggerable drug release, specifically focusing on ultrasound responsiveness.
• Conduct computational simulations using Coarse-Grained Molecular Dynamics (CGMD) to model nanoparticle properties.
• Perform empirical validation of simulated properties using in vitro studies and tumor-on-chip platforms.
• Collaborate with the SPARC consortium and industrial partners including Merck KGaA and Johnson & Johnson.

Requirements

• MSc or equivalent in Chemical Engineering, Pharmaceutical Sciences, Physical Chemistry, Biomedical Engineering, Nanotechnology, or a related field.
• Analytical mindset with the ability to bridge computational simulations and experimental validation.
• English proficiency required for academic communication, course participation, and thesis writing.
• Must be based in or able to relocate to the Netherlands.

Nice to have

• Experience in lipid-based nanoparticle formulations.
• Experience with coarse-grained molecular dynamic simulations.

Culture & Benefits

• 4-year employment period divided into two contracts (initial 1.5 years, then 2.5 years).
• Salary increases annually according to the Collective Labour Agreement for Dutch Universities.
• Additional 8% holiday allowance and an 8.3% end-of-year bonus.
• Access to the hirify.global Graduate School's professional development and mentoring programs.
• Comprehensive relocation support and a Dual Career Programme for partners.

Hiring process

• Application requires a detailed CV, Bachelor’s and Master’s transcripts, and a motivation letter.
• Final stages include a mandatory knowledge security risk assessment.